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TDP-43 and influenza mRNA, with Institut Pasteur, in Nucleic Acids Research
A collaboration with Nadia Naffakh's lab at Institut Pasteur maps the proteins bound to influenza mRNA and finds a role for TDP-43 in viral replication.
This study began during David’s Marie Skłodowska-Curie fellowship at Institut Pasteur and was completed as a co-led project between our two groups.
By mapping the RNA-binding proteins bound to influenza A virus mRNA (its “RBPome”), the team identified TDP-43 as a host protein involved in viral replication.
Read the paper: Dupont M, Krischuns T, et al., Courtney DG, Naffakh N. Nucleic Acids Research (2024). doi:10.1093/nar/gkae291
